# Reflective writing

In this reflective writing , I would like to agree or disagree & explain why ? And used examples in our day to day to respond to this reflective writing .

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You can cited a source if needed but it is not recommended

The Cox proportional hazard model is mainly used in medical research to show patient survival time when one or more variables are involved simultaneously. This allows an overview of the rate (hazard) of an event (death, etc.) to another factor (covariate).

“The Cox model is expressed by the hazard function denoted by h(t). Briefly, the hazard function can be interpreted as the risk of dying at time t. It can be estimated as follow:

h(t)=h0(t)×exp(b1x1+b2x2+…+bpxp)

where,

t represents the survival time

h(t) is the hazard function determined by a set of p covariates (x1,x2,…,xp)

the coefficients (b1,b2,…,bp) measure the impact (i.e., the effect size) of covariates.

the term h0 is called the baseline hazard. It corresponds to the value of the hazard if all the xi are equal to zero (the quantity exp(0) equals 1). The ‘t’ in h(t) reminds us that the hazard may vary over time.” (STHDA, n.d., para 11-12).

“In summary,

HR = 1: No effect

HR < 1: Reduction in the hazard

HR > 1: Increase in Hazard” (STHDA, n.d., para 16).

Example, hazard of death in a patient with multiple comorbidities (covariates) such as COPD, CHF, ESRD and expected survival rate.

References:

STHDA. (N.d.). Cox Proportional Hazards Model. http://www.sthda.com/english/wiki/cox-proportional-hazards-mode

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